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Which celebrities use peptides? Plenty of big names have said so in public, on podcasts, in magazines and on social media. Here is who said what, which peptide it was, and what the science actually shows. Plain words, with sources for every name.
- 25+ famous names on record
- 3 main kinds of peptide use
- 6 peptides backed by US advisers in July 2026
- 7 charts and tables
Many celebrities have said in public that they use peptides. They fall into three groups:
- Weight-loss shots. Ozempic, Wegovy, Mounjaro and Zepbound are peptides. Stars like Amy Schumer, Whoopi Goldberg, Sharon Osbourne and Meghan Trainor have named the one they used.
- Recovery peptides. Joe Rogan has said BPC-157 helped him heal an injury. RFK Jr. said on Rogan’s show that he used peptides on a couple of injuries.
- Beauty and anti-aging. Kris Jenner, Khloé Kardashian, Jennifer Aniston and Gwyneth Paltrow have all talked about peptide shots or peptide supplements.
Being famous does not make something proven. The weight-loss peptides have big trials behind them. Most of the others do not yet. Jump to the full who-said-what table for the quick view.
- What a peptide is
- The three groups
- Weight-loss shots
- The Kardashian-Jenner family
- Joe Rogan and the recovery crowd
- Beauty and anti-aging
- Timeline
- Why stars talk about it
- What the science shows
- What changed in the US in 2026
- Who said what: full table
- Claims to watch for
- What it means in Canada
- Picking a supplier
- Products
- Common questions
- Bottom line
- Sources
What a peptide is, in plain words
Your body builds things out of tiny pieces called amino acids. Think of them as beads.
String a few beads together and you get a peptide. String hundreds together and you get a protein. That is the only real difference: the length of the chain.
Your body already makes thousands of peptides. Some carry messages, like “you are full now” or “fix this cut.” Drug makers copy these messages to make medicines. Insulin is a peptide. So are the new weight-loss shots.
Growth hormone is often lumped in with peptides online. It is a full protein, about 12 times longer than tirzepatide.
Keep this chart in mind. When a celebrity says “peptides,” they could mean any of these. A weight-loss shot, a healing peptide and a beauty gummy are very different things.
The three groups of celebrity peptide use
When you sort every public statement we could find, almost all of them land in one of three groups.
1. Weight-loss shots
Ozempic, Wegovy, Mounjaro and Zepbound. These are prescription peptide medicines. This is by far the biggest group.
2. Recovery peptides
BPC-157 and TB-500, talked about for injuries and healing. Popular with podcasters and fighters.
3. Beauty and anti-aging
Peptide injections for skin, and peptide gummies or powders for hair. Popular with actors and reality stars.
This is our count from public statements, not a survey. Many more stars have been rumoured to use peptides. We left out anyone who has not said it themselves.
Group 1: The weight-loss shots
This is the group most people have heard about. Semaglutide (sold as Ozempic and Wegovy) and tirzepatide (sold as Mounjaro and Zepbound) are peptides. They copy gut hormones that tell your brain you are full.
Since late 2022, a long list of famous people have said they used one. A few examples, in their own words where we have them:
Amy Schumer
The comedian said in 2023 that she tried Ozempic and felt sick. In 2025 she said on Instagram that she uses Mounjaro. She has also said other stars lie about using these drugs.
Whoopi Goldberg
Said on The View in 2024 that she used Mounjaro, and talked about it again on Kelly Clarkson’s show.
Sharon Osbourne
Said she used Ozempic and lost a lot of weight. She also warned people to “be careful what you wish for.”
Meghan Trainor
The singer said in 2025 on Instagram that she used Mounjaro, along with diet and exercise changes.
Elon Musk
In late 2022 he wrote on social media that fasting and Ozempic or Wegovy helped him lose weight. That post helped make the drugs famous.
Oprah Winfrey
Told People magazine in 2023 that she uses a weight-loss medicine. She did not name which one.
Others who have named their drug include Tracy Morgan, Chelsea Handler, James Corden, Kathy Bates and Chrissy Teigen (Ozempic), and Jim Gaffigan, Charles Barkley and Rosie O’Donnell (Mounjaro). Harvey Fierstein named Zepbound. Serena Williams and Kelly Clarkson said they used a weight-loss medicine but did not say which.
Counted from the statements listed in the table below. Some stars switched drugs over time.
What about “Ozempic face”? You may have seen this phrase in celebrity news. It means a face that looks thinner or older after fast weight loss. It is not a special side effect of one drug. Losing a lot of weight quickly, in any way, can take fat out of the face too.
For how these weight-loss peptides compare with each other, see our semaglutide vs tirzepatide vs retatrutide guide.
The Kardashian-Jenner family
People search for “Kardashian peptides” a lot. Here is what the family has actually said, and what they have not.
Kris Jenner
On the SHE MD podcast in May 2026, she said she tried Ozempic once and it made her very sick. She said a peptide injection worked well for her instead, along with supplements like fish oil. She did not say which peptide.
Kris Jenner, part two
She has also said peptide hair gummies from a brand called Omi “pretty much changed my life.” She is a part owner of that brand, so keep that in mind.
Khloé Kardashian
In an August 2025 Instagram video, she said she had taken Omi hair peptides for months and called them the best thing for her hair. She is also a part owner of Omi.
Khloé and Ozempic
Khloé has said she did not use Ozempic for her weight loss. She said in late 2024 that she was only “mad” it did not exist ten years ago.
What about Kim? Kim Kardashian has talked about stem-cell shots in her scalp. Stem cells are not peptides, so we did not count her.
One more thing. A hair gummy is not the same as a peptide shot. Most peptides you swallow get broken down in your stomach, a lot like the protein in food. That does not mean the gummy does nothing. It means it works in a different way from an injection, and the two should not be compared.
Group 2: Joe Rogan and the recovery crowd
This group is where the word “peptides” really took off online. The star compound is BPC-157, a 15-bead peptide first found in stomach juice. It is studied for healing tendons, muscles and the gut.
Joe Rogan
Rogan has said BPC-157 helped heal an injury he had struggled with. A 2026 count found he has talked about BPC-157 in at least 31 episodes of his podcast.
Robert F. Kennedy Jr.
The US Health Secretary went on Rogan’s show in February 2026. He said he is “a big fan of peptides” and used them on a couple of injuries.
Andrew Huberman
The Stanford brain scientist has done whole episodes on peptides. He has pointed out that BPC-157 has lots of animal studies but very few human studies.
Derrick Lewis
The UFC fighter said in January 2026 that the UFC gave him “great peptides.” The UFC said that was wrong. Peptides like BPC-157 are banned in the UFC. The shots he got were allowed, tested products.
Recovery peptides are also popular with athletes. That is why sports bodies ban them. BPC-157 and TB-500 are on the World Anti-Doping list, so tested athletes cannot use them. Our BPC-157 vs TB-500 guide explains how the two differ.
Group 3: Beauty and anti-aging
This is the newest group, and it grew fast in 2025 and 2026.
Jennifer Aniston
In an interview reported in March 2026, the actor said she gets peptide shots every week. She said, “I do think that’s the future.” She did not name the peptide.
Gwyneth Paltrow
She told ELLE that shots of vitamin B12, NAD+ and peptides are among her biggest wellness tools. Note: NAD+ is not a peptide. It is a helper molecule found in every cell.
Neither star said which peptide. In skin care, the one people talk about most is GHK-Cu, a tiny 3-bead copper peptide found in blood. You can read more in our copper peptides and skin guide. Another is epitalon, a 4-bead peptide studied in the lab for aging. See our epitalon guide.
Timeline: how celebrity peptide talk grew
Red dots are weight-loss shots, gold dots are recovery or growth hormone, green dots are beauty.
Why celebrities talk about peptides
It helps to know why a famous person is talking before you trust what they say.
They own a piece of it
Kris Jenner and Khloé Kardashian are part owners of the hair peptide brand they praise. That is common in celebrity wellness.
Podcasts need topics
Long-form shows like Rogan’s and Huberman’s love new science stories. Peptides fit that perfectly.
They have private doctors
Stars often get treatments through personal doctors and pricey clinics. What they try is not a sign it is right for anyone else.
Honesty backlash
After years of rumours, some stars decided to just say it. Oprah said she was done with the shaming.
What the science actually shows
Here is the most important part of this guide. Not all peptides have the same amount of proof behind them.
A simplified guide. “Approved” means approved for certain medical uses by a regulator, not for every use a celebrity mentions.
A 2026 review in Psychology Today counted about 150 animal studies on BPC-157. Most came from one research group. There were only three human studies, with about 30 people in all. None of them compared BPC-157 with a dummy treatment. That kind of test is the gold standard.
So when Rogan or RFK Jr. says a peptide helped them, that is one person’s story. It might be true for them. But one story cannot tell you if it works, how well, or what the risks are. Injuries often heal on their own with time, and that can fool anyone.
The weight-loss peptides are the opposite. They have been tested in huge trials with a dummy shot for comparison. That is why doctors prescribe them.
What changed in the US in 2026
Celebrity talk and politics came together this year.
- 2023: US drug regulators put close to 20 peptides on a high-risk list. Pharmacies could no longer mix them for patients.
- February 2026: RFK Jr. said on Rogan’s show that he expected many of those peptides to come off the list.
- April 2026: Regulators agreed to review seven peptides.
- July 2026: An expert advisory panel voted to allow wider access to six of them.
This was a US decision about pharmacy mixing. It does not change the rules in Canada.
Not everyone cheered. Heart doctor Eric Topol said these peptides have no data on safety or how well they work. Timothy Caulfield, a health law expert at the University of Alberta, called the panel’s decision “tremendously frustrating.” He said the evidence does not support how hard peptides are being pushed.
Who said what: the full table
Every name in this guide in one place, with where they said it. Scroll sideways on a phone.
| Who | What they said | Group | Where and when |
|---|---|---|---|
| Amy Schumer | Tried Ozempic and felt sick; now uses Mounjaro | Weight loss | Watch What Happens Live, 2023; Instagram, 2025 |
| Whoopi Goldberg | Used Mounjaro | Weight loss | The View, 2024 |
| Sharon Osbourne | Used Ozempic | Weight loss | Interviews, 2023 |
| Meghan Trainor | Used Mounjaro | Weight loss | Instagram, 2025 |
| Elon Musk | Fasting plus Ozempic or Wegovy | Weight loss | Social media post, 2022 |
| Oprah Winfrey | Uses a weight-loss medicine (not named) | Weight loss | People, 2023 |
| Tracy Morgan | Used Ozempic | Weight loss | TODAY, 2023 |
| Chelsea Handler | Used Ozempic | Weight loss | Call Her Daddy podcast, 2023 |
| James Corden | Used Ozempic | Weight loss | Podcast, 2024 |
| Kathy Bates | Used Ozempic | Weight loss | People, 2024 |
| Chrissy Teigen | Used Ozempic | Weight loss | Podcast, 2025 |
| Jim Gaffigan | Used Mounjaro | Weight loss | People, 2024 |
| Charles Barkley | Used Mounjaro | Weight loss | His TV show |
| Rosie O’Donnell | Used Mounjaro | Weight loss | TikTok, 2024 |
| Harvey Fierstein | Used Zepbound | Weight loss | Page Six interview |
| Serena Williams | Used a GLP-1 medicine (not named) | Weight loss | TODAY interview |
| Kelly Clarkson | Uses a weight-loss medicine (not named) | Weight loss | Her talk show |
| Kris Jenner | Ozempic made her sick; a peptide injection worked for her; takes hair peptide gummies | Weight loss and beauty | SHE MD podcast, 2026; Page Six |
| Khloé Kardashian | Takes hair peptides; says she did not use Ozempic | Beauty | Instagram, 2025 |
| Jennifer Aniston | Gets weekly peptide shots | Beauty | Interview reported March 2026 |
| Gwyneth Paltrow | B12, NAD+ and peptide shots are key wellness tools | Beauty | ELLE |
| Joe Rogan | BPC-157 helped heal an injury | Recovery | His podcast |
| RFK Jr. | Used peptides on a couple of injuries | Recovery | Joe Rogan’s podcast, Feb 2026 |
| Andrew Huberman | Discussed peptides; noted few human studies | Recovery | Huberman Lab podcast |
| Derrick Lewis | Said the UFC gave him peptides; UFC said it did not | Recovery | Fight week, Jan 2026 |
| Sylvester Stallone | Used growth hormone (a protein) | Recovery | Time, 2008 |
Claims to watch for
“This star uses our product”
Be careful with ads that show a famous face. Many are fake. None of the stars in this guide have said they use any research peptide brand.
“Khloé lost weight on Ozempic”
She has said she did not. She credits years of workouts.
“If a celebrity uses it, it is proven”
Fame is not proof. Only good trials can show if something works and is safe.
“All peptides are the same”
A weight-loss shot, a healing peptide and a hair gummy are very different. Some have huge trials. Some have almost none.
“Peptides are steroids”
They are not. They work in a different way. Our guide on whether peptides are steroids explains.
“The US approved BPC-157”
No. A panel voted to allow wider pharmacy access. That is advice, not approval of a medicine.
What it means for people in Canada
Most of these stars live in the US. But their podcasts, shows and posts reach Canada every day. That is why searches for peptides keep growing here.
Some plain points to keep in mind:
- US rule changes do not cross the border. The July 2026 panel vote was about US pharmacies only.
- Weight-loss shots are prescription medicines here. Talk to your doctor or pharmacist.
- Research peptides are for labs. Compounds like BPC-157 are sold in Canada as research material, not as medicine.
- Stars have private doctors. Copying what a celebrity does, without that care, is a very different thing.
Canadian experts have asked for more caution too. Bob Hancock, a microbiologist at the University of British Columbia, said very few peptides have real, proven benefits. The honest view: a few peptides are proven medicines, many are promising in the lab, and most are not proven in people yet.
How to pick a research supplier
For lab research on peptides, the supplier matters as much as the compound. One US lab that tests peptides sold online found that at least 1 in 5 samples it checked were mislabeled.
- Find the test sheet first. No third-party lab report on the page means stop there.
- Check the report is real. A good report has a verify link you can check on the lab’s own site.
- Match the numbers. The amount on the report should match the label.
- Look for honest claims. Research sellers should not promise results in people or use celebrity faces. Shipping from Canada avoids customs trouble.
- Get the basics right. Clean bacteriostatic water and good maths. Our peptide calculator handles the maths.
For red flags, read our guide to spotting careless peptide suppliers in Canada. All of our lab reports are on our independent testing page. Members also get access to special pricing on some research vials. Log in or make an account to see what is on offer.
Products mentioned in this guide
Every item below ships from Canada with its third-party lab report on the product page. For research use only. Not for human use.
Keep reading
BPC-157 vs TB-500
The two recovery peptides, side by side.
Semaglutide vs tirzepatide vs retatrutide
The weight-loss peptides compared.
Growth hormone and anti-aging
What HGH is and what it is not.
Common questions
Which celebrities use peptides?
Many have said so in public. Weight-loss shots: Amy Schumer, Whoopi Goldberg, Sharon Osbourne, Meghan Trainor and Oprah. Recovery: Joe Rogan and RFK Jr. Beauty: Kris Jenner, Khloé Kardashian, Jennifer Aniston and Gwyneth Paltrow.
Does Joe Rogan use peptides?
Rogan has said BPC-157 helped heal an injury. He has talked about it in at least 31 podcast episodes.
Do the Kardashians use peptides?
Kris Jenner said a peptide injection worked well for her and takes hair peptide gummies. Khloé takes hair peptides. Both are part owners of the hair brand.
Is Ozempic a peptide?
Yes. Ozempic and Wegovy contain semaglutide, a peptide of 31 amino acids. Mounjaro and Zepbound contain tirzepatide, a peptide of 39.
What peptide does Jennifer Aniston use?
She said she gets weekly peptide shots and thinks they are the future. She has not said which peptide.
Did Khloé Kardashian use Ozempic?
She says no. In late 2024 she said she only wished it had existed ten years ago, and credits years of workouts.
What is Ozempic face?
A face that looks thinner or older after fast weight loss. It comes from losing face fat quickly, not from one drug in particular.
Are peptides safe because celebrities use them?
No. Fame is not proof. Weight-loss peptides have big trials behind them, but most healing and beauty peptides do not yet.
Is BPC-157 approved?
No. It is not an approved medicine in Canada or the US. A US panel voted in July 2026 for wider pharmacy access, which is not approval.
Do any of these celebrities use Red Leaf products?
No. None of them use, sell or endorse Red Leaf. We only report what they said in public, with sources.
Bottom line
Lots of celebrities have said in public that they use peptides. Most of them mean the weight-loss shots, like Ozempic and Mounjaro. Those have big trials behind them.
A smaller group, led by Joe Rogan and RFK Jr., talks about healing peptides like BPC-157. And stars like Kris Jenner and Jennifer Aniston talk about peptides for beauty. Those two groups have far less proof in people so far.
Fame gets a peptide attention. Only good research can tell you if it works. Keep those two things apart, and you will read celebrity news with clear eyes.
Every Red Leaf vial carries an independent lab report with a verify link, right on the product page. Free express shipping on Canadian orders over $250.
Browse the full catalogueSee our test sheetsSources
- Mosbergen D. Why 'anti-aging' peptide shots are trending on social media. Time, February 24, 2026. (Rogan, Paltrow, Aniston, Huberman, RFK Jr., Derrick Lewis; mislabeling testing.)
- Todd S. Why RFK Jr. backs peptides but questions vaccines. STAT News, April 6, 2026. (RFK Jr. on The Joe Rogan Experience, February 2026.)
- PBS NewsHour / Associated Press. FDA to weigh easing limits on unproven peptides favored by RFK Jr. and MAHA supporters. April 15, 2026.
- CBN News. As RFK Jr. and Rogan push to open door on peptides, FDA advisors recommend big shift. July 2026. (Six peptides backed by the Pharmacy Compounding Advisory Committee.)
- Tiller N. BPC-157: miracle drug or Joe Rogan experiment? Psychology Today, August 29, 2026.
- People via AOL. Kris Jenner claims Ozempic made her 'so sick' before finding peptides. May 8, 2026. (SHE MD Podcast.)
- AOL / Page Six. Kris Jenner says peptides 'changed my life'. 2026.
- NewBeauty. Khloé Kardashian takes these hair-growth peptides every morning. May 20, 2026.
- HELLO! Magazine. Khloé Kardashian breaks silence on Ozempic use. December 2024.
- HELLO! Magazine. Jennifer Aniston's anti-ageing peptide injections. March 13, 2026, citing The Wall Street Journal.
- ELLE via AOL. Gwyneth Paltrow on NAD+, peptide shots and Goop Kitchen. 2026.
- TODAY.com. Celebrities who've opened up about taking Ozempic or weight-loss drugs. Updated 2025.
- Fox News. Amy Schumer admits trying Ozempic. June 9, 2023. Fox News. Oprah Winfrey, Sharon Osbourne, Rosie O'Donnell admit using weight loss medication. 2024.
- Sports Illustrated. UFC clarifies after Derrick Lewis claims he was given peptides. January 19, 2026.
- Voice of America. Stallone admits to using growth hormone for latest Rambo role. January 26, 2008.
- Huberman A. Huberman Lab podcast episodes on peptide therapeutics, 2024.
- CP24 / Canadian Press. Peptides are rising in popularity, but health experts warn very few have any benefits. July 30, 2026.
- Semrush keyword data, Canada database, September 2026.
Research use only. BPC-157, retatrutide, tirzepatide, GHK-Cu, epitalon, NAD+ and every other compound sold by Red Leaf Research Labs are laboratory materials for in-vitro research. They are not approved for treatment, injection, ingestion or any human or animal use. Nothing on this page is medical advice, a dose, or a protocol. Celebrity statements are reported from public sources for information only and are not endorsements of Red Leaf. Brand names belong to their owners. Full wording on our legal terms page.
