Glutathione research: quick summary
Glutathione is a tripeptide thiol, L-gamma-glutamyl-L-cysteinyl-glycine, supplied by Red Leaf Research Labs as a 1500 mg lyophilized research material in the reduced form, GSH. Published work studies it as one half of the GSH/GSSG redox couple and as a cosubstrate for glutathione peroxidases and transferases. It is not an authorized medicine in Canada, is not a supplement or food, is for laboratory research use only, is not for human or veterinary use, and carries no dosing or protocol information.
Glutathione Canada: Glutathione 1500mg Research Product
Reduced glutathione is stocked in a 1500 mg lyophilized fill for qualified laboratory purchasers in Canada, described here by material, lot paperwork and dispatch terms.
People reach this page through buy glutathione Canada, glutathione peptide Canada and L-glutathione reduced Canada. The third is the precise phrase: the oxidized dimer is a different material. Anyone arriving from a personal-health motive should speak with a clinician.
Red Leaf Research Labs supplies glutathione as a research chemical. It is not supplied to be given to any person or animal, no dosing accompanies it, and nothing is claimed for what it does.
Glutathione 1500mg Research Format and Options
| Attribute | Detail |
|---|
| Research format | One vial, 1500 mg L-glutathione reduced |
| Physical state | White dried solid in a sealed glass vial |
| Analytical documentation | Independent report keyed to the lot, methods included |
| Fulfilment | Domestic shipping to research addresses |
| Intended use | Laboratory research only; not for human or veterinary use |
The 1500 mg quantity is a stock unit, not a recommendation, and no guidance is given on how much an experiment needs.
Glutathione Research Specifications
- Compound name: L-glutathione, reduced
- Alternative name(s): GSH, reduced glutathione, L-gamma-glutamyl-L-cysteinylglycine
- Research shorthand: GSH
- Compound class: Tripeptide thiol
- Pathway interest: GSH/GSSG redox couple; cosubstrate for glutathione peroxidases and transferases
- Structural origin: Glutamate, cysteine and glycine, joined by a gamma-linkage from the glutamate side chain
- CAS: 70-18-8
- Molecular formula: C10H17N3O6S
- Molecular weight: approximately 307.3 g/mol
- Physical format: Dried solid, freeze-dried
- Available research quantity: 1500 mg per vial
- Intended use: Laboratory research use only
- Fulfilment: Domestic shipping in Canada
What Is Glutathione?
Glutathione is a three-residue peptide with one defining peculiarity. The bond between glutamate and cysteine is formed from the glutamate side-chain carboxyl rather than the alpha-carboxyl, a gamma-linkage that ordinary peptidases do not cleave. The molecule is therefore built by two dedicated enzymes, glutamate-cysteine ligase and glutathione synthetase, rather than by translation, and its reactive group is the cysteine thiol.
Glutathione is most often confused with three neighbours. Oxidized glutathione, GSSG, is the disulfide-linked dimer, a separate compound with its own CAS number. S-acetyl-L-glutathione is a derivative. N-acetylcysteine is a modified amino acid, not a peptide. A report on any of these describes nothing about reduced GSH.
Glutathione and Redox Pathway Research
Glutathione appears in the literature mainly through its thiol. Two GSH molecules can be oxidized to the disulfide GSSG, and the ratio between the forms is a standard index of cellular redox state, measured in cell and tissue extracts by chromatographic and mass spectrometric methods. In enzymology it is a cosubstrate rather than a catalyst: glutathione peroxidases use it as an electron donor in reducing hydroperoxides, and glutathione transferases use it as a nucleophile in conjugation reactions studied in xenobiotic metabolism. Further work covers protein S-glutathionylation, glutaredoxin-mediated de-glutathionylation and the mitochondrial glutathione pool.
All of that describes measurements in cell extracts, purified enzyme systems, cultured cells and animal tissue. A cosubstrate relationship or a redox ratio measured in a model system does not establish that any effect occurs in a person.
Why Buy Glutathione 1500mg in Canada from a Domestic Research Supplier?
Route length is the first consideration and 1500 mg makes it a large one: a gram and a half of a thiol exposed to an undocumented hold.
The second is that the useful question on any lot here, how much remains reduced, is one for the supplier, and easier to press within one legal system.
Both are contract points. Neither changes what an assay would return.
How This Glutathione Canada Page Improves on Typical Competitor Listings
Many listings for this compound borrow supplement copy, and consumer claims come with it. This page differs in five ways.
- The copy describes the actual structure, including the gamma-linkage that distinguishes it from an ordinary tripeptide.
- The analytical basis is stated, not asserted: a report tied to the lot and its methods.
- The page asserts no outcome, benefit or safety property, qualified or plain.
- The regulatory framing is explicit: this is neither an authorized medicine nor a consumer product.
- The oxidized form and common derivatives are named, so a purchaser can see what this is not.
How to Evaluate a Glutathione Certificate of Analysis
Two questions here are peculiar to the molecule. One is redox state: the reduced tripeptide and its disulfide dimer are different compounds with different registry numbers. The other is the gamma linkage, invisible to amino acid analysis, since acid hydrolysis returns glutamate, cysteine and glycine either way.
- Compound identity: L-glutathione, reduced, against CAS 70-18-8, the gamma-glutamyl linkage named.
- Lot reference: the lot on the certificate is the lot on the container.
- Analysis date: the testing date, ageing fastest on an oxidisable thiol.
- Test methods: the assay named, oxidised content measured separately.
- Measured quantity: the 1500 mg reconciled with what the document covers.
- Purity result: the value returned and the method behind it.
- Laboratory verification: the analysing laboratory named, with its vendor relationship.
A certificate giving one purity figure and nothing on oxidised content leaves the lot’s most time-sensitive property undescribed.
Glutathione 1500mg Lyophilized Research Format
The container holds a freeze-dried solid: frozen, then dried by sublimation under vacuum. For most peptides that is about hydrolysis. Here it is as much about oxygen, water being how it reaches the cysteine thiol.
Oxidation of that thiol to the disulfide is the chemistry the literature associates with this compound, faster at alkaline pH and catalysed by trace metals. The solid is hygroscopic, and a 1500 mg container is opened many times, each an exposure event. How it is kept is for the receiving laboratory to specify; nothing is prescribed here.
How to Buy Glutathione in Canada for Qualified Research
- Confirm eligibility. Verify your organization may receive research chemicals for the work intended.
- Review documentation. Read the lot report before ordering, noting oxidised content.
- Select quantity. Decide how many 1500 mg containers the plan needs.
- Check shipping route. Confirm route and transit window against receiving hours.
- Record receipt. Log the lot, arrival date and appearance of the solid.
These steps concern purchasing and records, not dosing or design.
Glutathione Availability in Canada: Research vs. Consumer Searches
Glutathione is unusual in this catalogue because it is sold widely outside the laboratory. Oral supplements, topical products and clinic services all carry the name, and search results mix those markets together.
A research chemical is a different category of goods from all of them. This vial has not been assessed by Health Canada for use in a person, carries no licensed labelling, and is not manufactured or documented to any consumer-product standard.
A personal-health interest in glutathione belongs with a licensed clinician.
Glutathione 1500mg Canada Procurement Checklist
| Check | What to confirm |
|---|
| Purpose | Laboratory research in an organization eligible to receive it |
| Identity | L-glutathione reduced, CAS 70-18-8, gamma-glutamyl bond |
| Distinctness | The reduced tripeptide, not GSSG, S-acetyl-glutathione or NAC |
| Quantity | Number of containers, allowing for repeated opening |
| Documentation | Lot report giving oxidised content as a separate determination |
| Verification | Whether a thiol assay is run independently on arrival |
| Handling | Dry sealed receiving for a hygroscopic, oxidisable solid |
Explore Glutathione Research Information
Background reading: what third-party testing does and does not tell a purchaser, the terminology reference, and buying research peptides in Canada in 2026.
Glutathione research FAQ
Does Red Leaf Research Labs provide dosing information?
No. No dosing, reconstitution, concentration, route or protocol information is provided.
Working out concentration for this vial? Our peptide reconstitution calculator converts vial size and bacteriostatic water volume into mg per mL and U-100 syringe units.
What is the difference between GSH and GSSG?
GSH is the reduced form with a free cysteine thiol; GSSG is the oxidized dimer joined by a disulfide bond. They are separate compounds with separate CAS numbers.
Is this the same as a glutathione supplement?
No. This is a laboratory research chemical, not a supplement or medicine, and is not supplied for any use in a person.
Why is glutathione called a peptide if it is not made by ribosomes?
It is a peptide by structure: three residues joined by amide bonds. The glutamate linkage is a gamma-linkage, so two dedicated enzymes assemble it instead.
What documentation comes with the 1500mg vial?
A third-party report is available for the current lot, by lot number, with the methods used.
Research use only. Glutathione 1500 mg is supplied strictly for laboratory research. It is not an authorized medicine in Canada, is not a supplement or food, is not for human or veterinary use, and carries no dosing or protocol information. Anyone with a personal-health question about glutathione should consult a licensed clinician.
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